Metal-Catalyzed Reactions for Energy and Biomedical Applications
DOI:
https://doi.org/10.71222/akkwke66Keywords:
metal catalysis, energy conversion, electrocatalysis, biomedical applications, single-atom catalysts, coordination polymersAbstract
Metal-catalyzed reactions have emerged as cornerstone technologies bridging energy conversion systems and biomedical therapeutics through their remarkable selectivity, efficiency, and tunability. This review examines the dual convergence of metal catalysis in addressing critical challenges in sustainable energy production and advanced healthcare delivery. The discussion encompasses single-atom catalysts, dual-metal site architectures, and coordination polymer frameworks that enable transformative processes including electrocatalytic carbon dioxide reduction, fuel cell oxygen reduction, hydrogen evolution, and targeted therapeutic interventions. Recent advances in biohybrid catalysis and metal-organic frameworks have demonstrated unprecedented control over reaction pathways and biological interactions, creating opportunities for integrated solutions to energy sustainability and human health challenges. Through analysis of catalyst design principles, mechanistic understanding, and structure-activity relationships, this work illustrates how strategic manipulation of metal centers, ligand environments, and support materials drives performance optimization across both domains. The synthesis of knowledge from energy catalysis and catalytic biomedicine reveals common design strategies and emerging opportunities for cross-disciplinary innovation that will shape future development of multifunctional metal-based systems capable of addressing interconnected global challenges in climate, energy security, and healthcare accessibility.
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Copyright (c) 2025 Jessica Lin, Michae Chen (Author)
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