New Generation Drug Delivery Systems: Nanocarriers, Smart Hydrogels, and Organelle Targeting Technologies

Zhichao Wang

doi:10.71222/btmzw826

Authors

Zhichao Wang St George's College, University of London, London, United Kingdom Author

DOI:

https://doi.org/10.71222/btmzw826

Keywords:

drug delivery, nanocarriers, smart hydrogels, organelle targeting, precision medicine

Abstract

The field of drug delivery has undergone significant advancements with the emergence of novel technologies such as nanocarriers, smart hydrogels, and organelle-targeting systems. These innovations enable more precise, efficient, and controlled delivery of therapeutic agents, enhancing drug efficacy while minimizing side effects. Nanocarriers, including lipid nanoparticles and polymeric nanoparticles, improve drug solubility and stability, allowing for controlled release and targeted delivery to specific tissues or cells. Smart hydrogels, responsive to environmental stimuli like pH and temperature, offer sustained drug release and site-specific targeting, making them ideal for chronic disease treatment. Organelle-targeting technology, which directs drugs to cellular organelles such as mitochondria and lysosomes, has emerged as a cutting-edge approach to precision medicine. These technologies hold the potential to address challenges like poor drug solubility, non-specific distribution, and treatment resistance. However, challenges remain, including biocompatibility, long-term stability, and scalability. Future research will focus on overcoming these hurdles and integrating these technologies to create personalized and efficient drug delivery systems. The development of multi-functional, hybrid systems combining nanocarriers, hydrogels, and organelle targeting will pave the way for more effective, targeted therapies.

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